• Zenease Holistic REM Sleep Support bottle, 90 capsules, with a few capsules in front
  • Zenease supplement facts panel with quality badges: GMP, gluten-free, non-GMO, made in USA, 3rd-party lab tested, vegan
  • Zenease bottle with a green sleep mask on an open book — faster sleep onset, deeper restorative sleep, calmer nights
  • The Power Trio: Sleeproot, Holixer and KSM-66 Ashwagandha — clinically studied ingredients, woman holding Zenease bottle in bed
  • Total holistic sleep solution infographic: calm and relaxation, stress and cortisol balance, sleep cycle support, mineral foundations
  • Racing mind at night? Infographic on how Zenease helps quiet a busy nervous system
  • Supports your body&
  • Clinically studied ingredients, evidence-informed dosages, no fairy dusting — Zenease bottle beside a glass of water, 1% for the Planet
  • Why people choose Zenease: calmer nervous system, deeper sleep, no melatonin or habit-forming ingredients
  • Formulated with intention: ingredient list with the purpose of each — Sleeproot, Holixer, KSM-66, saffron, GABA, L-Theanine, magnesium, zinc, L-Tryptophan, B6
  • The saffron difference: standardized saffron extract 30 mg on a marble counter
  • Exhausted but still can&
  • Hormones stealing your sleep? Adaptogens and mineral support for deeper, uninterrupted sleep
  • Two bottles of Zenease Holistic REM Sleep Support, 90 capsules each
1 13

Zenease® Sleep Support Supplement

$24.95
$24.95
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Zenease® offers an elite, multi-pathway solution for comprehensive sleep support, specifically formulated for adults seeking a clean, non-habit-forming rest. This premium, U.S.-sourced blend leverages clinically studied ingredients like KSM-66 Ashwagandha and Holixer Holy Basil to lower cortisol and quiet racing thoughts. By combining deep-sleep minerals—including Magnesium Glycinate and Zinc—with a calming complex of L-Theanine, Valerian Root, and GABA, our melatonin-free formula promotes faster sleep onset, uninterrupted rest, and a refreshed, jitter-free morning.

Benefits
  • Supports Natural Melatonin Production: Formulated with L-Tryptophan and active Vitamin B6 (P5P) to help your body naturally produce serotonin and melatonin—no synthetic melatonin added.
  • Wake Up Refreshed with Saffron-Powered Sleep: Our sleep formula features saffron bulb extract, a natural plant ingredient shown to promote relaxation, reduce stress, and support deeper, more restorative sleep - so you fall asleep easier, stay asleep longer, and wake up feeling energized and ready for your day.
  • Fall Asleep Faster & Stay Asleep Longer: Clinically studied Valerian Root, GABA, and L-Theanine help calm the nervous system, reduce sleep latency, and support deeper, uninterrupted sleep.
  • Stress Relief for a Calm Mind at Night: Features organic KSM-66® Ashwagandha and Holixer™ Holy Basil to help lower cortisol, quiet racing thoughts, and support relaxation before bedtime.
  • Deep, Restorative Sleep for Next-Day Energy: Magnesium Glycinate and Zinc Bisglycinate support sleep quality, muscle relaxation, and overnight recovery—wake up refreshed, not groggy.
Quality
  • Premium, Science-Backed Sleep Formula: Multi-pathway blend with clinically studied, branded ingredients at evidence-informed doses—designed for adults seeking clean, non-habit-forming sleep support.
  • U.S. made with trusted U.S. suppliers: Zenease is proudly manufactured in the United States in a GMP-certified facility, using globally sourced high-quality ingredients from trusted u.s. suppliers. Every batch is third-party tested to ensure exceptional quality.
  • Your purchase goes beyond personal wellness: it supports the planet, too. Zen Principle is a proud member of 1% for the Planet, donating 1% of every sale to environmental causes that protect our air, water, and ecosystems. Together, we’re making wellness better for you and the world.
    Zenease Holistic REM Sleep Support bottle, 90 capsules, with a few capsules in front
    Zenease supplement facts panel with quality badges: GMP, gluten-free, non-GMO, made in USA, 3rd-party lab tested, vegan
    Zenease bottle with a green sleep mask on an open book — faster sleep onset, deeper restorative sleep, calmer nights
    The Power Trio: Sleeproot, Holixer and KSM-66 Ashwagandha — clinically studied ingredients, woman holding Zenease bottle in bed
    Total holistic sleep solution infographic: calm and relaxation, stress and cortisol balance, sleep cycle support, mineral foundations
    Racing mind at night? Infographic on how Zenease helps quiet a busy nervous system
    Supports your body&
    Clinically studied ingredients, evidence-informed dosages, no fairy dusting — Zenease bottle beside a glass of water, 1% for the Planet
    Why people choose Zenease: calmer nervous system, deeper sleep, no melatonin or habit-forming ingredients
    Formulated with intention: ingredient list with the purpose of each — Sleeproot, Holixer, KSM-66, saffron, GABA, L-Theanine, magnesium, zinc, L-Tryptophan, B6
    The saffron difference: standardized saffron extract 30 mg on a marble counter
    Exhausted but still can&
    Hormones stealing your sleep? Adaptogens and mineral support for deeper, uninterrupted sleep
    Two bottles of Zenease Holistic REM Sleep Support, 90 capsules each

    Ingredients

    Frequently Asked Questions

    How long does it take to feel the effects?

    Many customers report feeling relaxed within 30 to 60 minutes. Because the formula supports natural sleep pathways rather than acting as a sedative, timing can vary based on factors like stress, caffeine intake, and evening routines.

    Who is this sleep supplement best for?

    It’s ideal for adults with stress-related sleep issues, trouble falling asleep, or waking during the night who want a non-habit-forming, melatonin-free sleep aid.

    Does this product contain melatonin?

    No. This formula is completely melatonin-free. Instead, it supports the body’s natural melatonin production using L-Tryptophan and active Vitamin B6 (P5P).

    Can this be taken nightly?

    Yes. The ingredients are commonly used in daily sleep support supplements and are suitable for regular nightly use as directed.

    How does this supplement help with stress or racing thoughts at night?

    It includes clinically studied Ashwagandha KSM-66® and Holy Basil (Holixer™), which help support healthy cortisol levels and promote calmness and relaxation before bedtime.

    More questions? Get more answers on our FAQs page.

     Frequently Asked Questions